Skin changes during chemotherapy: how to protect it and relieve sensitivity

When you begin chemotherapy treatment, your body undergoes a profound transformation. The skin, our largest organ, is often one of the first to reflect these changes.

It's normal to feel that your skin no longer reacts the same way; intense dryness, tightness, redness, or a sensitivity that wasn't there before may appear. It's not just about aesthetics; skin discomfort can affect daily well-being , sleep, and even mood.

Understanding what is happening in the skin barrier allows you to adapt your routine and reduce many of these discomforts.

What happens to the skin barrier during chemotherapy?

During chemotherapy, treatments not only attack cancer cells but also healthy cells , including those in the epidermis. This can weaken the skin barrier and impair its protective capacity.

As a result, many patients find their skin becomes more sensitive to factors that didn't previously affect them, such as temperature changes, cosmetic products, or even contact with clothing. Furthermore, chemotherapy can disrupt the production of natural oils, causing the skin to lose hydration and elasticity. The result is more fragile, reactive skin that is prone to dehydration.

These changes are common and are part of the body's response to treatment. The good news is that, with an adapted routine, it's possible to alleviate many of these discomforts.

How to identify what your skin needs at this stage?

During chemotherapy, we don't talk about classic skin types , but rather temporary manifestations that require an immediate response. Identifying what you're feeling at any given moment is key to effectively relieving discomfort.

Intense dryness and a feeling of tightness

It is the most common symptom; the skin becomes rough, dull, or cracked due to a lack of natural lipids.

• The solution : prioritize rich , emollient, and nourishing creams that lock in moisture. Ingredients like glycerin and ceramides are great allies for restoring comfort.
• Tip : Avoid very hot water and always wear cotton clothing to reduce friction.

La Roche Posay

LIPIKAR BAUME LIGHT AP+M triple-action repair balm

Body moisturiser

From £ 18.75

WATCH NOW

Avène

XERACALM AD baume relipidant

Body moisturiser

From £ 20.04

WATCH NOW

Sensitivity, redness or itching

Your skin reacts to even the slightest external stimuli. Here, the golden rule is "less is more".

• The solution : replace your usual gel with syndet cleansing oils (soap-free) that respect the skin's balance and soothe from the shower.
• Tip : Always pat dry gently with a towel and avoid formulas containing alcohol or perfumes.

Eucerin

PH5 Body Body Shower Oil

Shower gel

From £ 12.96

WATCH NOW

Avène

XERACALM A.D. huile lavante relipidante

Facial cleanser

From £ 13.38

WATCH NOW

Fragility and flaking

Some people notice visible peeling or especially vulnerable areas that need intensive repair.

• The solution : apply repairing balms with soothing agents such as panthenol or centella asiatica, which help to restore the skin barrier.
• Tip : Never remove the skin manually or rub the area; let the active ingredients do their work with repeated applications.

La Roche Posay

CICAPLAST BAUME B5+ soothing ultra-repairing balm

Face moisturizer

From £ 7.68

WATCH NOW

Avène

CICALFATE crème réparatrice

wounds - scars - Nappy creams and powders - Body moisturiser

From £ 8.64

WATCH NOW

Increased sensitivity to the sun and risk of blemishes

During chemotherapy, the skin can become more reactive to sunlight, even with brief exposure. This increases the risk of irritation and the appearance of dark spots.

• The solution : Use broad-spectrum SPF50+ sun protection daily, even on cloudy days or if you are indoors in natural light.
• Tip : Reapply every few hours if there is direct exposure and prioritize lightweight, fragrance-free formulas tested on sensitive skin.

Isdin

fusion water magic SPF50 PHOTOPROTECTOR

Sunscreen for face

From £ 18.80

WATCH NOW

Avène

SOLAIRE HAUTE PROTECTION unscented fluid SPF50+

Sunscreen for face

From £ 12.58

WATCH NOW

Daily routine to care for your skin during chemotherapy

Ultra-gentle cleaning

Start your day by removing impurities with pH-balanced formulas that cleanse gently. Warm water will be your best tool to avoid stripping away your skin's protective oils.

Frequent hydration

Don't wait until your skin feels tight. Apply your moisturizer several times a day, especially after bathing, taking advantage of the fact that your skin still retains some moisture to improve absorption.

Daily sun protection

Even if you have already chosen your appropriate sunscreen , incorporate it as the last step each morning to strengthen the barrier against external aggressions.

Cosmetic minimalism

Avoid exfoliants, retinoids, or harsh acids. The fewer unnecessary stimuli your skin receives, the more energy it will have to maintain its balance.

When to seek medical advice and why follow-up is important

Every cancer treatment is different, and every skin responds in its own way. What provides relief for one person may not be enough for another.

If persistent pain, severe irritation or deep cracks, signs of infection, intense inflammation, or any reaction that does not improve with basic care appears, it is essential to consult with the medical or dermatological team that is assisting you.

Cosmetics can soothe, protect, and provide support, but they never replace clinical follow-up. If you have any concerns, professional evaluation is always the priority.

Taking care of your skin is also taking care of yourself

During chemotherapy, self-care takes on a different meaning. Taking a few minutes each day to moisturize and protect your skin isn't a superficial gesture: it's a way to gently and respectfully attend to your needs.

A simple, personalized routine can become a little moment of yourself within your day. It's not about perfection, but about consistency and listening to what your skin needs.

Taking care of yourself means reminding yourself that, even in this process, your well-being remains the priority.